Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Quercetin
500 mg
†
Top Medical Research Studies
9.5
We explored the effects of quercitrin on platelet activation to better understand its role in blood clotting. Through comprehensive experiments—like assessing platelet aggregation and thrombus formation—we observed that quercitrin significantly hinders platelet activation. This means it impairs platelet aggregation and granule secretion, which are crucial in forming blood clots.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Read More
8
We investigated how quercetin, a natural compound, can guard against the harmful effects of extracellular histones on platelets. Our study involved evaluating the interaction between histones and platelets in animal and lab settings.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
Read More
8
SXS shows promise against blood stasis
We investigated how Shi-Xiao-San, a traditional Chinese herbal formula, affects blood stasis, which relates to conditions like thrombosis and coronary heart disease. Through advanced techniques, we identified over 45 compounds, such as quercetin, that may play crucial roles in reducing blood viscosity and improving vascular health. Our tests showed that Shi-Xiao-San works by influencing key pathways involved in blood flow and inflammation. While promising, further studies are necessary to fully understand its mechanisms and benefits for treating blood clotting disorders.
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Most Useful Reviews
9
Improved circulation
19 people found this helpful
After taking three tablets, my condition improved significantly, alleviating my hyperlipidaemia and angina pectoris. I experienced headaches and shoulder stiffness, but overall, my circulation feels better. I recommend it, especially for elderly individuals dealing with blood clot risks.
Read More
9
Blood sugar lowered
2 people found this helpful
Quercetin has successfully lowered my fasting blood sugar. Despite following a low-carb diet, nothing had as significant an impact as taking 500 mg of Quercetin three times daily. I’m pleasantly surprised by these results.
Read More
7.5
Preventing blood clots
This excellent remedy, which I use alongside curcumin to thin the blood and help prevent blood clots, has improved my health. My health analyses have shown better results since I take birth control pills as well.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9.5
We explored the effects of quercitrin on platelet activation to better understand its role in blood clotting. Through comprehensive experiments—like assessing platelet aggregation and thrombus formation—we observed that quercitrin significantly hinders platelet activation. This means it impairs platelet aggregation and granule secretion, which are crucial in forming blood clots.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Read More
9
Quercetin as anticoagulant examined
We investigated the potential of quercetin, a compound from the African eggplant, to act as an anticoagulant. By using various methods including bioassay-guided fractionation, we studied its effects on blood clotting in mice. Our experiments revealed promising anticoagulant activities.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
Read More
9
Taxifolin inhibits NETosis, aids thrombo-inflammation
We investigated how taxifolin, a bioactive flavonoid, could impact diseases associated with blood clots like lupus and antiphospholipid syndrome (APS). Using in vitro assays and mouse models, we observed that taxifolin significantly inhibits the formation of neutrophil extracellular traps—an action known as NETosis—linked to inflammation and clotting. Notably, taxifolin reduced autoantibody formation and large-vein thrombosis in these models. This pioneering study suggests that taxifolin may offer protective benefits against thrombo-inflammatory conditions, making it an exciting area for further research.
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9
We explored how Baiying Qingmai Formulation (BF) affects thromboangiitis obliterans (TAO) by analyzing its chemical makeup and how it interacts with various signaling pathways.
Our findings showed that BF significantly inhibits important proteins related to inflammation and blood clotting. It not only decreases harmful cytokines but also increases protective metabolites in the bloodstream.
Ultimately, we believe BF offers a promising path to alleviate symptoms of TAO by reducing blood clots and improving vascular health in affected individuals.
Our findings showed that BF significantly inhibits important proteins related to inflammation and blood clotting. It not only decreases harmful cytokines but also increases protective metabolites in the bloodstream.
Ultimately, we believe BF offers a promising path to alleviate symptoms of TAO by reducing blood clots and improving vascular health in affected individuals.
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We closely examined a retrospective study focused on how a blend of micronized flavonoids, including quercetin, can alleviate symptoms of grade II and III hemorrhoidal disease.
Patients taking this compound showed a notable 89.8% success rate in reducing hemorrhoid severity after just one week of treatment.
Improvements were seen across a range of symptoms with no reported side effects. Overall, this study suggests that quercetin, alongside other ingredients, may effectively help manage hemorrhoidal symptoms safely.
Patients taking this compound showed a notable 89.8% success rate in reducing hemorrhoid severity after just one week of treatment.
Improvements were seen across a range of symptoms with no reported side effects. Overall, this study suggests that quercetin, alongside other ingredients, may effectively help manage hemorrhoidal symptoms safely.
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User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved circulation
19 people found this helpful
After taking three tablets, my condition improved significantly, alleviating my hyperlipidaemia and angina pectoris. I experienced headaches and shoulder stiffness, but overall, my circulation feels better. I recommend it, especially for elderly individuals dealing with blood clot risks.
Read More
9
Blood sugar lowered
2 people found this helpful
Quercetin has successfully lowered my fasting blood sugar. Despite following a low-carb diet, nothing had as significant an impact as taking 500 mg of Quercetin three times daily. I’m pleasantly surprised by these results.
Read More
7.5
Preventing blood clots
This excellent remedy, which I use alongside curcumin to thin the blood and help prevent blood clots, has improved my health. My health analyses have shown better results since I take birth control pills as well.
Read More
2
No effect observed
I bought Quercetin primarily for its purported benefits on blood vessels and to address my second-degree varicose veins. However, I haven’t noticed any change in my legs. I believe only a surgeon or laser treatment can aid my situation now.
Read More
Frequently Asked Questions
9
Improved circulation
19 people found this helpful
After taking three tablets, my condition improved significantly, alleviating my hyperlipidaemia and angina pectoris. I experienced headaches and shoulder stiffness, but overall, my circulation feels better. I recommend it, especially for elderly individuals dealing with blood clot risks.
2
No effect observed
I bought Quercetin primarily for its purported benefits on blood vessels and to address my second-degree varicose veins. However, I haven’t noticed any change in my legs. I believe only a surgeon or laser treatment can aid my situation now.
9
Blood sugar lowered
2 people found this helpful
Quercetin has successfully lowered my fasting blood sugar. Despite following a low-carb diet, nothing had as significant an impact as taking 500 mg of Quercetin three times daily. I’m pleasantly surprised by these results.
7.5
Preventing blood clots
This excellent remedy, which I use alongside curcumin to thin the blood and help prevent blood clots, has improved my health. My health analyses have shown better results since I take birth control pills as well.
8
We investigated whether quercetin, along with other flavonoids, impacts platelet activity, which is crucial for blood clotting. Using blood samples from healthy volunteers, we looked at how these compounds influence the activation states of platelets through a specialized laboratory technique.
Our findings showed that quercetin and the other flavonoids demonstrated significant antiplatelet activity, effectively blocking a key receptor involved in platelet aggregation. This work helps shed light on how these natural compounds may play a role in preventing cardiovascular issues by reducing unwanted blood clot formation.
Our findings showed that quercetin and the other flavonoids demonstrated significant antiplatelet activity, effectively blocking a key receptor involved in platelet aggregation. This work helps shed light on how these natural compounds may play a role in preventing cardiovascular issues by reducing unwanted blood clot formation.
7
We explored the effects of polyphenols, specifically quercetin, on the bioenergetics and function of platelets under conditions of normoglycemia and acute hyperglycemia. Our study evaluated how these compounds can impact platelet activity that typically increases due to high blood sugar levels.
We found that the use of polyphenols like quercetin helps lessen heightened platelet activity caused by hyperglycemia. This suggests that quercetin might play a role in reducing clot formation risk for patients with diabetes.
Overall, polyphenols have promising potential in thrombosis prevention, but further research is likely needed to fully understand their benefits.
We found that the use of polyphenols like quercetin helps lessen heightened platelet activity caused by hyperglycemia. This suggests that quercetin might play a role in reducing clot formation risk for patients with diabetes.
Overall, polyphenols have promising potential in thrombosis prevention, but further research is likely needed to fully understand their benefits.
9
Quercetin as anticoagulant examined
We investigated the potential of quercetin, a compound from the African eggplant, to act as an anticoagulant. By using various methods including bioassay-guided fractionation, we studied its effects on blood clotting in mice. Our experiments revealed promising anticoagulant activities.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
4
We explored the potential of quercetin as a treatment related to COVID-19, especially its role in managing blood clotting. The research highlights that quercetin can help reduce coagulation issues, particularly in patients suffering from COVID-19, by inhibiting certain proteins involved in clot formation. However, while quercetin shows promise in this area, the evidence does not firmly establish its effectiveness as a definitive treatment for blood clots in COVID-19 patients. Further investigation is necessary to clarify its benefits in clinical settings.
8
We investigated how quercetin, a natural compound, can guard against the harmful effects of extracellular histones on platelets. Our study involved evaluating the interaction between histones and platelets in animal and lab settings.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
References
- Dai J, He W, Liu SA, Huang S, He X, et al. Rapid screening of the antithrombotic active components of Ledeb with thrombin binding affinity ultrafiltration mass spectroscopy. Anal Methods. 2025;17:2046. 10.1039/d4ay01909a
- Manikanta K, NaveenKumar SK, Hemshekhar M, Thushara RM, Mugesh G, et al. Quercetin inhibits platelet activation and ER-stress mediated autophagy in response to extracellular histone. Phytomedicine. 2025;138:156386. 10.1016/j.phymed.2025.156386
- Gauer JS, Ajanel A, Kaselampao LM, Candir I, MacCannell ADV, et al. Plant-derived compounds normalize platelet bioenergetics and function in hyperglycemia. Res Pract Thromb Haemost. 2024;8:102548. 10.1016/j.rpth.2024.102548
- Gogoi D, Chattopadhyay P, Dolui SK, Khan MR, Mukherjee AK. Studies on in vivo antithrombotic activity of quercetin, a natural flavonoid isolated from a traditional medicinal plant, African eggplant (Solanum indicum). J Ethnopharmacol. 2024;335:118686. 10.1016/j.jep.2024.118686
- Rysenga CE, May-Zhang L, Zahavi M, Knight JS, Ali RA. Taxifolin inhibits NETosis through activation of Nrf2 and provides protective effects in models of lupus and antiphospholipid syndrome. Rheumatology (Oxford). 2024;63:2006. 10.1093/rheumatology/kead547
- Fan W, Lan S, Yang Y, Liang J. Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huang-Qi-Gui-Zhi-Wu-Wu decoction against deep vein thrombosis. J Orthop Surg Res. 2023;18:475. 10.1186/s13018-023-03948-6
- Zou C, Liu L, Huang C, Hu S. Baiying qingmai formulation ameliorates thromboangiitis obliterans by inhibiting HMGB1/RAGE/NF-κB signaling pathways. Front Pharmacol. 2022;13:1018438. 10.3389/fphar.2022.1018438
- Wei X, Gao M, Sheng N, Yao W, Bao B, et al. Mechanism investigation of Shi-Xiao-San in treating blood stasis syndrome based on network pharmacology, molecular docking and in vitro/vivo pharmacological validation. J Ethnopharmacol. 2023;301:115746. 10.1016/j.jep.2022.115746
- Hu M, Peng X, Shi S, Wan C, Cheng C, et al. Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification. J Mater Chem B. 2022;10:8218. 10.1039/d2tb01704k
- Liao X, Zhuang X, Liang C, Li J, Flaumenhaft R, et al. Flavonoids as Protein Disulfide Isomerase Inhibitors: Key Molecular and Structural Features for the Interaction. J Agric Food Chem. 2022;70:4475. 10.1021/acs.jafc.1c07994
- Gravina AG, Pellegrino R, Facchiano A, Palladino G, Loguercio C, et al. Evaluation of the Efficacy and Safety of a Compound of Micronized Flavonoids in Combination With Vitamin C and Extracts of , , and for the Reduction of Hemorrhoidal Symptoms in Patients With Grade II and III Hemorrhoidal Disease: A Retrospective Real-Life Study. Front Pharmacol. 2021;12:773320. 10.3389/fphar.2021.773320
- Manjunath SH, Thimmulappa RK. Antiviral, immunomodulatory, and anticoagulant effects of quercetin and its derivatives: Potential role in prevention and management of COVID-19. J Pharm Anal. 2022;12:29. 10.1016/j.jpha.2021.09.009
- Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, et al. Virus-induced senescence is a driver and therapeutic target in COVID-19. Nature. 2021;599:283. 10.1038/s41586-021-03995-1
- Zaragozá C, Monserrat J, Mantecón C, Villaescusa L, Álvarez-Mon MÁ, et al. Binding and antiplatelet activity of quercetin, rutin, diosmetin, and diosmin flavonoids. Biomed Pharmacother. 2021;141:111867. 10.1016/j.biopha.2021.111867
- Rojas-Garbanzo C, Rodríguez L, Pérez AM, Mayorga-Gross AL, Vásquez-Chaves V, et al. Anti-platelet activity and chemical characterization by UPLC-DAD-ESI-QTOF-MS of the main polyphenols in extracts from Psidium leaves and fruits. Food Res Int. 2021;141:110070. 10.1016/j.foodres.2020.110070
- Oh TW, Do HJ, Jeon JH, Kim K. Quercitrin inhibits platelet activation in arterial thrombosis. Phytomedicine. 2021;80:153363. 10.1016/j.phymed.2020.153363
